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In the application of this medicatio in conjunction with digoxin it may be necessary to reduce both the saturation and maintenance dose of the latter.

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however, serum digoxin concentration should be interpreted in the clinical context.

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by contrast, approximately 20 of subjects in the digoxin group showed a severe tritan defect table 2 2 .

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based on table 5, a patient in heart failure with an estimated lean body weight of 70 kg and a c cr of 60 ml min should be given a dose of 250 mcg daily of digoxin tablets, usually taken after the morning meal.

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therefore, future study is warranted to investigate the effect of other individual diuretics in combination with digoxin on the risk of digoxin intoxication.
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Older adults should usually receive low doses of digoxin because higher doses may cause serious side effects.

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